No stranger to drama, A.J. Pierzynski found himself at the center of it again. This time, he didn’t mind.

Pierzynski led off the 10th inning with his second homer of the game and the Chicago White Sox beat the Cleveland Indians 6-5 Wednesday night for their seventh straight win.

“Ozzie was yelling at me to not try to be a hero and hit a single,” Pierzynski said. “When I hit it, I was like, its got a chance. But I didn’t know it was going to make it.”

It did, giving the White Sox a three-game sweep and their second 10-inning win in as many nights.

Pierzynski always seems to find himself at the center of the action for the White Sox, from reaching base on a controversial dropped third strike against the Los Angeles Angels in the 2005 playoffs to fighting with former Cubs catcher Michael Barrett in 2006.

This type of attention he’ll take.

Masa Kobayashi (4-4) pitched a perfect ninth before Pierzynski drove the first pitch of the 10th out to left-center for his seventh homer. Teammates mobbed Pierzynski as he crossed the plate.

Adam Russell (2-0) worked the 10th for his second win in as many nights and the second of his career.

C.C. Sabathia allowed five runs and seven hits in eight innings for Cleveland. The reigning AL Cy Young Award winner struck out five and walked two.

The last-place Indians have lost five straight and are 12 1/2 games back of the White Sox in the AL Central. They could look to deal Sabathia if they continue to lag behind in the division, with the big left-hander eligible for free agency at the end of the season.

“I’m just worrying about day to day pitching,” Sabathia said. “I get the ball and that’s it.”

Grady Sizemore hit two solo homers for Cleveland, tying it at 5 with a drive off Scott Linebrink in the ninth.

“I made a bad pitch tonight and he got it,” Linebrink said. “You can’t make mistakes to him. You certainly don’t want to put him on the bases to lead off an inning in a close ballgame like that because you put him on the bases, the next thing you know he’s on second in scoring position. You want to be aggressive and go after him. It was a changeup up in the zone and he hit it. I’ve got to make a better pitch right there.”

Pierzynski and Jermaine Dye went deep in the first inning and Nick Swisher singled in a run in the second to give Chicago a 3-2 lead.

Sizemore walked and scored on Jamey Carroll’s triple in the fifth and connected in the sixth to put the Indians ahead, but Sabathia ran into trouble in the seventh.

Pablo Ozuna led off the inning with a grounder to third baseman Casey Blake, whose wild throw allowed Ozuna to reach second. Alexei Ramirez lined a one-out infield single off Blake’s glove and Brian Anderson followed with a two-run double to left-center.

Nick Masset was in line for his first win after pitching a scoreless seventh, but with closer Bobby Jenks getting the night off because of soreness in his left side, the White Sox turned to Linebrink in the ninth. He blew his second save in as many chances when Sizemore connected.

“I thought we did a good job of taking the momentum back our way,” Sizemore said. “Obviously it was still a tie game but I thought we had the momentum. I was confident we were going to win.”